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Description
Overview of Briganix 90mg Tablets
Composition: Contains Brigatinib 90mg.
– Substitutes: Trepmac, Alunbrig.
– Shipping Class: Room Temperature.
Uses
– Primary Use: Treats a specific type of lung cancer known as non-small cell lung cancer (NSCLC) by inhibiting the growth of cancer cells.
Side Effects
–Common Side Effects: May include nausea, vomiting, diarrhea, loss of appetite, abdominal pain, constipation, fatigue, dizziness, fever, headaches, insomnia, or joint pain. If these persist or worsen, contact a healthcare professional.
How to Use
-Administration Instructions: Take orally with or without food as prescribed by a healthcare provider. Swallow tablets whole without crushing or chewing.
Mechanism of Action
–Function: Acts as an anaplastic lymphoma kinase (ALK) inhibitor, demonstrating significant effectiveness in treating ALK-positive NSCLC.
Important Information
– Monitoring for Pulmonary Reactions: Watch for symptoms of interstitial lung disease/pneumonitis, especially within the first week of treatment.
– Blood Pressure Management: Manage blood pressure before starting treatment; monitor after two weeks and monthly thereafter.
– Heart Rate Monitoring: Be aware of potential bradycardia; monitor heart rate and blood pressure regularly.
– Visual Disturbances: Report any changes in vision.
– Muscle Health: Increased creatine phosphokinase (CPK) levels can occur; report unexplained muscle symptoms and monitor CPK levels.
– Pancreatic Enzymes: Monitor lipase and amylase levels due to potential increases.
– Blood Sugar Levels: Assess and monitor fasting serum glucose; adjust antihyperglycemic medications as needed.
Warnings and Precautions
– Alcohol: May exacerbate dizziness or vision issues; limit alcohol consumption.
– Pregnancy: Potential to harm the fetus; evaluate risks and benefits.
– Lactation: Not recommended due to potential risk to the infant; consult a doctor before breastfeeding.
– Driving: Exercise caution due to possible dizziness or vision blur.
– Kidney Function: Use cautiously in patients with kidney disease; monitor kidney function closely.
– Liver Function: Use cautiously in patients with liver disease; monitor liver function closely.
Missed Dose Guidance
– If a dose is missed, skip it and continue with the next dose at the regular schedule. Do not double the dose.
