Description
Buy Imbruvica (Ibrutinib) 140 mg Online
Indications: Imbruvica (Ibrutinib) 140 mg is prescribed for various hematologic cancers, including chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), mantle cell lymphoma (MCL), Waldenström’s macroglobulinemia (WM), marginal zone lymphoma (MZL), and chronic graft-versus-host disease (cGVHD).
Pharmacology: Ibrutinib inhibits Bruton’s tyrosine kinase (BTK), a crucial signaling molecule in B-cell receptor pathways, essential for malignant B-cell survival and proliferation.
Dosage and Administration: The standard dose is 140 mg once daily, preferably taken at the same time daily, with or without food.
Interactions: Ibrutinib may interact with medications metabolized by CYP3A4 and CYP2D6 enzymes, necessitating disclosure of all medications to healthcare providers.
Side Effects: Common side effects include diarrhea, fatigue, musculoskeletal pain, nausea, rash, bruising, and upper respiratory tract infections. Serious effects may include bleeding, infections, atrial fibrillation, hypertension, and liver toxicity.
Precautions and Warnings: Patients should be monitored for increased bleeding and infections, as well as atrial fibrillation, hypertension, and liver toxicity risks.
Overdose Effects: Overdose management involves supportive measures, as there’s no specific antidote. Treatment focuses on addressing symptoms.